Saier Chemical
1 / 2
1,2,3-Triazole is a very attractive group. It has high aromatic stability, metabolic stability, the presence of hydrogen bonds leads to good binding ability with biological target molecules, and has good solubility, which can improve the deficiencies of the original drug molecules in solubility, pharmacodynamics, and pharmacokinetic. With the introduction of "Click Chemistry", 1,2,3-triazole compounds were synthesized regionally and selectively through 1,3-dipolar cycloaddition reaction. This method has the advantages of simplicity, reliability, high yield, high selectivity, and easy separation. Due to these characteristics, Huisgen-Click reaction has been widely used in many fields.
| Melting Point | 23-25°C (lit.) |
| Boiling Point | 203°C @ 752mm Hg (lit.) |
| Density | 1.192 g/ml at 25°C (lit.) |
| Flash Point | 225°F |
| Proportion | 1.192 |
| Form | Liquid |
| Packaging | 200L HDPE drums, 200L Iron drums |
1,2,3-triazole is an important structural unit of many drug molecules and has a wide range of biological activities, such as antibacterial, antiviral, and anti-tumor. For example, some compounds containing 1,2,3-triazole structure have an inhibitory effect on HIV reverse transcriptase and can be used in the development of anti-AIDS drugs.
1,2,3-triazole can be used to prepare functional materials. For example, by introducing it into polymers through a "click reaction", the properties of polymers can be improved, such as improving their thermal stability, mechanical properties and solubility. In addition, it can also be used to prepare liquid crystal materials, fluorescent materials, etc.
1,2,3-triazole is an important intermediate in organic synthesis and can be used to construct various complex organic molecular structures. By reacting with different reagents, different functional groups can be introduced to achieve diversified modification of the compound structure.
1,2,3-triazole is irritating to the eyes, skin and respiratory tract. Avoid direct contact during use and wear appropriate protective equipment, such as gloves and goggles. If it accidentally comes into contact with the skin or eyes, rinse immediately with plenty of water and seek medical attention in time.
It should be stored in a sealed container in a cool, dry place, away from fire and oxidants, and should not be mixed with strong acidic or alkaline substances.
